Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170620 | 0.87 | NOS2 (0.41) | NOS2NAMPTHRH2ACACB | |
| SCHEMBL2169022 | 0.80 | NOS2 (0.37) | NOS2NAMPTHRH2ACACB | |
| SCHEMBL26763693 | 0.65 | NOS2 (0.49) | NOS2ALDH1A1ACACBKDM4E | |
| SCHEMBL2170780 | 0.64 | ALDH1A1 (0.36) | NOS2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL12477383 | 0.62 | NOS2 (0.43) | NOS2NAMPTLMNA | |
| SCHEMBL4762505 | 0.62 | NOS2 (0.42) | NOS2NAMPTLMNA | |
| SCHEMBL20233602 | 0.61 | NAMPT (0.48) | NOS2NAMPT | |
| SCHEMBL30872565 | 0.61 | NOS2 (0.44) | NOS2NAMPTLMNAACACBCYP1A2 | |
| SCHEMBL5907334 | 0.60 | NOS2 (0.45) | NOS2NAMPTLMNA | |
| SCHEMBL25593244 | 0.59 | POLB (0.45) | NOS2ALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | NOS2 671/4885NAMPT 794/4885ALDH1A1 516/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | NOS2 671/4885NAMPT 794/4885ALDH1A1 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.