SCHEMBL2170817

SCHEMBL2170817

Cc1[c]ccc2c1CC(C)O2

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
MAPT P10636 1/20 0.43
KDM4E B2RXH2 4/20 0.38
MAOA P21397 4/20 0.35
MAOB P27338 3/20 0.35
BRD4 O60885 3/20 0.34
CREBBP Q92793 3/20 0.34
POLL Q9UGP5 1/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PBRM1 Q86U86 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
PARP1 P09874 1/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10772041 0.80 MAOA (0.40) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL10528478 0.73 ALDH1A1 (0.34) ALDH1A1HPGDMAPTKDM4E
SCHEMBL15399383 0.67 RAB9A (0.45) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL4596846 0.64 KDM4E (0.43) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL5543882 0.64 BRD4 (0.45) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL20482181 0.64 BRD4 (0.41) ALDH1A1HPGDMAPTMAOAMAOB
SCHEMBL13894882 0.64 AKR1B1 (0.42) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL3694108 0.64 BRD4 (0.41) ALDH1A1HPGDMAPTKDM4EMAOA
SCHEMBL1387744 0.64 TDP1 (0.47) ALDH1A1MAPTKDM4EMAOAMAOB
SCHEMBL1285321 0.64 PARP1 (0.45) ALDH1A1HPGDMAPTKDM4EMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703007-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2014-04-22 US disclosed
US-20110180511-A1 Polishing Composition and Polishing Method Using the Same FUJIMI INCORPORATED (JP) 2011-07-28 US disclosed