Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708751 | 0.93 | KMT2A (0.33) | RIPK1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL21708723 | 0.90 | RIPK1 (0.36) | RIPK1ALDH1A1GAALMNAHPGD | |
| SCHEMBL21708781 | 0.86 | KMT2A (0.39) | L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL21708675 | 0.83 | CCR1 (0.37) | ALDH1A1GAALMNAHPGDKDM4E | |
| SCHEMBL21708518 | 0.83 | TAS1R3 (0.32) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL21708545 | 0.81 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21708602 | 0.81 | SMN1; SMN2 (0.33) | ALDH1A1HPGDL3MBTL1KDM4ETP53 | |
| SCHEMBL21656297 | 0.79 | RIPK1 (0.39) | RIPK1ALDH1A1GAALMNAHPGD | |
| SCHEMBL21708777 | 0.79 | KMT2A (0.38) | ALDH1A1GAAHPGDKMT2AMEN1 | |
| SCHEMBL21631984 | 0.77 | KDM4E (0.44) | RIPK1ALDH1A1GAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |