Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | USP9X | Q93008 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708449 | 0.93 | RIPK1 (0.36) | KMT2AMEN1ALDH1A1LMNARIPK1 | |
| SCHEMBL21708518 | 0.89 | TAS1R3 (0.32) | KMT2ATAS1R3TAS1R1MEN1HSD17B10 | |
| SCHEMBL21708675 | 0.87 | CCR1 (0.37) | KMT2ATAS1R3TAS1R1MEN1ALDH1A1 | |
| SCHEMBL21708723 | 0.83 | RIPK1 (0.36) | KMT2AMEN1ALDH1A1LMNARIPK1 | |
| SCHEMBL21708777 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL21708781 | 0.81 | KMT2A (0.39) | KMT2ATAS1R3TAS1R1HTTNPSR1 | |
| SCHEMBL21708792 | 0.79 | TAS1R3 (0.33) | KMT2ATAS1R3TAS1R1MEN1LMNA | |
| SCHEMBL21708755 | 0.79 | KMT2A (0.38) | KMT2ATAS1R3TAS1R1MEN1ALDH1A1 | |
| SCHEMBL21708626 | 0.79 | L3MBTL1 (0.30) | — | |
| SCHEMBL21708728 | 0.78 | KMT2A (0.39) | KMT2AALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |