Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708792 | 0.93 | TAS1R3 (0.33) | TSHRKMT2AMEN1 | |
| SCHEMBL21708770 | 0.90 | PTGFR (0.35) | SMN1; SMN2PTGFRALDH1A1L3MBTL1KDM4E | |
| SCHEMBL21708747 | 0.85 | TAS1R3 (0.36) | SMN1; SMN2PTGFRL3MBTL1TSHRKMT2A | |
| SCHEMBL21708612 | 0.82 | TAS1R3 (0.32) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL21708646 | 0.82 | NISCH (0.37) | ALDH1A1L3MBTL1KDM4ETSHRHPGD | |
| SCHEMBL21708613 | 0.81 | TAS1R3 (0.33) | PTGFR | |
| SCHEMBL21708449 | 0.81 | RIPK1 (0.36) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL21656205 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL21708787 | 0.78 | HPGD (0.39) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL21631976 | 0.76 | GABBR2 (0.50) | PTGFRKDM4ETSHRITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |