SCHEMBL21708563

SCHEMBL21708563

CCCC(F)OC(=O)CCC(C#N)c1c(Cl)ccc(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21708626 0.88 L3MBTL1 (0.30)
SCHEMBL21708723 0.87 RIPK1 (0.36) MEN1KMT2A
SCHEMBL21708561 0.87 CCR1 (0.30) MEN1KMT2A
SCHEMBL21708518 0.86 TAS1R3 (0.32) MEN1KMT2A
SCHEMBL21708678 0.85
SCHEMBL21708545 0.83 KMT2A (0.33) KMT2A
SCHEMBL21708615 0.81 PTGFR (0.35) MEN1KMT2A
SCHEMBL21708569 0.81 KMT2A (0.33) KMT2A
SCHEMBL21656305 0.81 RAPGEF3 (0.33)
SCHEMBL21632095 0.79 PTGFR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3609870-A1 SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2020-02-19 EP disclosed
EP-3609869-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2020-02-19 EP disclosed