Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.39 |
| ▸ | PGR | P06401 | 6/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708724 | 0.93 | NR3C2 (0.35) | NR3C1NR3C2PGRTAS1R3TAS1R1 | |
| SCHEMBL21708670 | 0.88 | MEN1 (0.36) | TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL21708754 | 0.84 | — | — | |
| SCHEMBL21708769 | 0.82 | TAS1R3 (0.34) | TAS1R3TAS1R1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21708672 | 0.82 | NR3C1 (0.36) | NR3C1NR3C2TAS1R3TAS1R1 | |
| SCHEMBL21656580 | 0.81 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL21632105 | 0.79 | NR3C1 (0.46) | NR3C1NR3C2PGR | |
| SCHEMBL21708659 | 0.77 | SLC6A3 (0.32) | L3MBTL1 | |
| SCHEMBL21708795 | 0.77 | TAS1R3 (0.33) | TAS1R3TAS1R1 | |
| SCHEMBL21708772 | 0.77 | PTGFR (0.34) | NR3C1NR3C2PGRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |