Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708725 | 0.86 | SMN1; SMN2 (0.35) | KMT2ASMN1; SMN2GAA | |
| SCHEMBL21708743 | 0.84 | MEN1 (0.41) | TAS1R3TAS1R1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL21708769 | 0.83 | TAS1R3 (0.34) | TAS1R3TAS1R1PTGFRTSHRKMT2A | |
| SCHEMBL21708772 | 0.82 | PTGFR (0.34) | TAS1R3TAS1R1PTGFRKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21708672 | 0.81 | NR3C1 (0.36) | TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL21708632 | 0.81 | PTGFR (0.33) | TAS1R3TAS1R1PTGFRKMT2ASMN1; SMN2 | |
| SCHEMBL21708652 | 0.81 | TAS1R3 (0.34) | TAS1R3TAS1R1 | |
| SCHEMBL21656118 | 0.80 | MTNR1A (0.41) | PTGFRKMT2ANPC1SMN1; SMN2KAT6A | |
| SCHEMBL21631951 | 0.79 | PTGFR (0.46) | PTGFRKMT2ANPC1SMN1; SMN2GAA | |
| SCHEMBL21708773 | 0.76 | TAS1R3 (0.33) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |