Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708773 | 0.92 | TAS1R3 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL21708725 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ALMNAMEN1TAAR1 | |
| SCHEMBL21708691 | 0.81 | LMNA (0.36) | SMN1; SMN2KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL21656361 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAPTGFRPOLBTAAR1 | |
| SCHEMBL21708779 | 0.79 | NPC1 (0.33) | KMT2APTGFRALDH1A1TDP1GAA | |
| SCHEMBL21631949 | 0.76 | PTGFR (0.43) | SMN1; SMN2KMT2ALMNAPTGFRTAAR1 | |
| SCHEMBL21708771 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL21708674 | 0.74 | ADRB2 (0.33) | KMT2ALMNAMEN1TAS1R3TAS1R1 | |
| SCHEMBL21708655 | 0.72 | MEN1 (0.38) | KMT2ALMNAMEN1ALDH1A1GAA | |
| SCHEMBL21656189 | 0.69 | CTSS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |