Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708602 | 0.85 | SMN1; SMN2 (0.33) | PTGFRTSHRKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL21708643 | 0.84 | POLB (0.45) | TAS1R3TAS1R1NPSR1GAATSHR | |
| SCHEMBL21708694 | 0.82 | TAS1R3 (0.37) | TAS1R3TAS1R1PTGFRGABRA1GABRG2 | |
| SCHEMBL21708781 | 0.81 | KMT2A (0.39) | TAS1R3TAS1R1PTGFRNPSR1TSHR | |
| SCHEMBL21708580 | 0.81 | KMT2A (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21708613 | 0.80 | TAS1R3 (0.33) | TAS1R3TAS1R1PTGFR | |
| SCHEMBL21708792 | 0.80 | TAS1R3 (0.33) | TAS1R3TAS1R1TSHRKMT2A | |
| SCHEMBL21631909 | 0.80 | GAA (0.50) | PTGFRNPSR1GAATSHRKMT2A | |
| SCHEMBL21656364 | 0.79 | MTNR1A (0.40) | PTGFRNPSR1JAK2HSP90AA1RAB9A | |
| Hydrochloric Acid SCHEMBL21708784 | 0.79 | GAA (0.37) | TAS1R3TAS1R1PTGFRGAACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |