Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708670 | 0.83 | MEN1 (0.36) | KMT2AMEN1TSHRATMTAS1R3 | |
| SCHEMBL21708655 | 0.80 | MEN1 (0.38) | KMT2AMEN1TSHRATMTAS1R3 | |
| SCHEMBL9009606 | 0.79 | NPSR1 (0.44) | KMT2AMEN1TSHRATMGAA | |
| SCHEMBL21708674 | 0.77 | ADRB2 (0.33) | KMT2AMEN1TAS1R3TAS1R1CTSS | |
| SCHEMBL21656569 | 0.76 | GAA (0.39) | KMT2AMEN1TSHRATMGAA | |
| SCHEMBL21632076 | 0.74 | KMT2A (0.44) | KMT2AMEN1ATMGAALMNA | |
| SCHEMBL21708743 | 0.74 | MEN1 (0.41) | KMT2AMEN1TSHRATMTAS1R3 | |
| SCHEMBL21708649 | 0.73 | NR3C1 (0.39) | TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL21708691 | 0.73 | LMNA (0.36) | KMT2AGAALMNARAB9ASMN1; SMN2 | |
| SCHEMBL21708724 | 0.73 | NR3C2 (0.35) | TAS1R3TAS1R1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |