SCHEMBL21709151

SCHEMBL21709151

C#CCNCC(OCC#C)c1cc(O)c(O)cc1C#C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.32
KDM1A O60341 2/20 0.32
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709250 0.89 MAOA (0.32) MAOAKDM1AMAOB
SCHEMBL21709266 0.83 P2RX3 (0.34) MAOA
SCHEMBL21709246 0.83 KDM1A (0.32) KDM1A
SCHEMBL21709149 0.80 ADRB2 (0.33)
SCHEMBL21708881 0.79 MAOA (0.33) MAOAKDM1A
SCHEMBL21709154 0.79 TSHR (0.30)
SCHEMBL21709152 0.79 ADRA1A (0.41) MAOAKDM1AMAOB
SCHEMBL21708868 0.77 MAPT (0.41) MAOA
SCHEMBL21709143 0.76
SCHEMBL21708891 0.73 KDM1A (0.35) MAOAKDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed