SCHEMBL21709249

SCHEMBL21709249

C#CCOc1cc(C(O)CN(CC#C)CC#C)c(C#C)cc1O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709244 0.91 MAOA (0.32) MAOA
SCHEMBL21709248 0.85
SCHEMBL21709161 0.84 ADRB2 (0.31)
SCHEMBL21708902 0.83 ADRA2A (0.35)
SCHEMBL21709274 0.79 P2RX3 (0.33) MAOA
SCHEMBL21708891 0.78 KDM1A (0.35) MAOA
SCHEMBL21709219 0.78 MAOA (0.31) MAOA
SCHEMBL21709057 0.77 CYP3A4 (0.40) MAOA
SCHEMBL21709218 0.75 MAOA (0.31) MAOA
SCHEMBL21708854 0.74 CGAS (0.33) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed