Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 16/20 | 0.73 |
| ▸ | TAS1R1 | Q7RTX1 | 16/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28010260 | 0.91 | TAS1R3 (0.61) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21078060 | 0.85 | HTT (0.71) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL702662 | 0.84 | TAS1R3 (1.00) | TAS1R3TAS1R1HPGDHTTALDH1A1 | |
| SCHEMBL12706057 | 0.84 | ALDH1A1 (0.73) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13169591 | 0.84 | TAS1R3 (0.70) | TAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL21078080 | 0.83 | TAS1R3 (0.58) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28863365 | 0.83 | MEN1 (0.53) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20878559 | 0.83 | TAS1R3 (0.69) | TAS1R3TAS1R1 | |
| SCHEMBL178377 | 0.81 | MEN1 (0.59) | TAS1R3TAS1R1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5756487 | 0.81 | TAS1R3 (0.88) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885MEN1 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.