Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 14/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 14/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223871 | 0.93 | TAS1R3 (0.63) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL12471407 | 0.90 | TAS1R3 (0.58) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL22747924 | 0.86 | PRSS1 (0.59) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL165896 | 0.86 | PRSS1 (0.61) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL15146792 | 0.85 | HTT (0.68) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL21711047 | 0.84 | TAS1R3 (0.73) | TAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL1003282 | 0.84 | RAB9A (0.82) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL7152139 | 0.83 | TAS1R3 (0.55) | TAS1R3TAS1R1RAB9ANPC1CTRB1 | |
| SCHEMBL12366265 | 0.82 | NPC1 (0.69) | TAS1R3TAS1R1RAB9ANPC1ALDH1A1 | |
| SCHEMBL13350409 | 0.82 | TAS1R3 (0.66) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| CN-101917980-A | Amine derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2010-12-15 | — | — | CN | disclosed |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | TAS1R3 4504/4885TAS1R1 4692/4885RAB9A 3717/4885 |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | TAS1R3 4504/4885TAS1R1 4692/4885RAB9A 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.