Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989453 | 0.87 | RIPK1 (0.42) | CYP4A11CYP4F2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30109148 | 0.87 | RIPK1 (0.42) | CYP4A11CYP4F2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21715585 | 0.86 | FAAH (0.47) | CTSKCTSSPPARGPPARA | |
| SCHEMBL391263 | 0.85 | P2RY2 (0.47) | MAPTCTSKPPARGPPARA | |
| SCHEMBL4714695 | 0.84 | CTSK (0.51) | MAPTCTSKATMCTSS | |
| SCHEMBL21714668 | 0.84 | CTSK (0.51) | MAPTCTSKATMCTSS | |
| SCHEMBL31269567 | 0.83 | LOXL2 (0.45) | CYP3A4CYP2C9CYP2C19TSHRMAPT | |
| SCHEMBL30109275 | 0.83 | LOXL2 (0.45) | CYP3A4CYP2C9CYP2C19TSHRMAPT | |
| SCHEMBL31269590 | 0.83 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19TSHRMAPT | |
| SCHEMBL2793090 | 0.82 | CYP2D6 (0.44) | POLBCYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836761-B2 | Cinchonine-derived catalysts and methods of using same | BRANDEIS UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20200048243-A1 | CINCHONINE-DERIVED CATALYSTS AND METHODS OF USING SAME | BRANDEIS UNIVERSITY (US) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836761-B2 | Cinchonine-derived catalysts and methods of using same | MCM2, MCM7, MCM5 | CYP4A11 1016/4885CYP4F2 1329/4885POLB 57/4885 |
| US-20200048243-A1 | CINCHONINE-DERIVED CATALYSTS AND METHODS OF USING SAME | MCM2, MCM7, MCM5 | CYP4A11 1016/4885CYP4F2 1329/4885POLB 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.