Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 7/20 | 0.41 |
| ▸ | CES2 | O00748 | 6/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171577 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL11603666 | 0.91 | CYP1A2 (0.40) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL11603662 | 0.91 | CYP1A2 (0.40) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL6129938 | 0.84 | CYP1A2 (0.42) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL6129937 | 0.84 | CYP1A2 (0.42) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL11538903 | 0.81 | CES2 (0.43) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL11538905 | 0.81 | CES2 (0.43) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL24914463 | 0.79 | ATM (0.38) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL11682865 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1CES1CES2 | |
| SCHEMBL21747960 | 0.79 | AKT1 (0.43) | ALDH1A1CES1CES2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812960-A | Corrosion-resistant and ageing-resistant PP rope for submarine cable and production process thereof | 无锡市恒龙电缆材料有限公司 | 2024-10-22 | — | — | CN | claimed |
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | claimed |
| US-20230059747-A1 | A COOLING PREPARATION | SYMRISE AG (DE) | 2023-02-23 | — | — | US | claimed |
| EP-3982910-A1 | A COOLING PREPARATION | Symrise AG (DE) | 2022-04-20 | — | — | EP | claimed |
| WO-2020249216-A1 | A COOLING PREPARATION | SYMRISE AG (DE) | 2020-12-17 | — | — | WO | claimed |
| US-9743685-B2 | Mixtures having improved cooling effect | SYMRISE AG (DE) | 2017-08-29 | — | — | US | claimed |
| EP-2849718-B1 | MIXTURES HAVING IMPROVED COOLING EFFECT | SYMRISE AG (DE) | 2017-02-01 | — | — | EP | claimed |
| US-9139714-B2 | Method for producing dialkylphosphinic acids and esters and salts thereof by means of allyl alcohols-acroleins and use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-09-22 | — | — | US | claimed |
| US-20150139918-A1 | MIXTURES HAVING IMPROVED COOLING EFFECT | SYMRISE AG (DE) | 2015-05-21 | — | — | US | claimed |
| EP-2849718-A2 | MIXTURES HAVING IMPROVED COOLING EFFECT | Symrise AG (DE) | 2015-03-25 | — | — | EP | claimed |
| US-4247718-A | Process for the preparation of α-β unsaturated alcohols | STAMICARBON, B.V. (NL) | 1981-01-27 | — | — | US | claimed |
| US-4209542-A | Process for augmenting or enhancing the aroma or taste of a foodstuff by adding to a foodstuff a mixture of 1-acyl-2,6,6-trimethylcyclohexene derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-06-24 | — | — | US | claimed |
| EP-0004122-A2 | Process for the preparation of alpha,beta-unsaturated alcohols | STAMICARBON B.V. (NL) | 1979-09-19 | — | — | EP | claimed |
| US-4103036-A | Flavoring with derivatives of 1-acetyl-3,3-dimethylcyclohexane, and processes for using same and processes for preparing said 1-acetyl-3,3-dimethylcyclohexane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-07-25 | — | — | US | claimed |
| US-4093752-A | FOODSTUFFS, CHEWING GUM, TOOTHPASTE, MEDICINES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-06-06 | — | — | US | claimed |
| US-4089986-A | FOODS, TOOTHPASTE, CHEWING GUM, DRUGS, PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-16 | — | — | US | claimed |
| US-4084009-A | 4-HYDROXY-2,4,6,6-TETRAMETHYLCYCLOHEX-2-ENE-1-ONE, ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-04-11 | — | — | US | claimed |
| US-4068012-A | FLAVORS, PERFUMES, TOBACCO | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-01-10 | — | — | US | claimed |
| US-4053657-A | FOODS AND FLAVOR USE OF 1-(3,3-DIMETHYL-2-NORBORNYL-2-PROPANONE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-10-11 | — | — | US | claimed |
| US-4000329-A | Flavoring compositions and foods containing one or more alkyl side chain methyl substituted or unsubstituted 2,2,6-trimethyl-1-cyclohexen-1-vinyl alkanoates | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-12-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059747-A1 | A COOLING PREPARATION | GPX4, HTR3C, ADH1C | ALDH1A1 153/4885MAPK1 3384/4885TDP1 1456/4885 |
| US-20150139918-A1 | MIXTURES HAVING IMPROVED COOLING EFFECT | BCL2A1, HSPE1, BCL2 | ALDH1A1 418/4885MAPK1 423/4885TDP1 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.