SCHEMBL2171695

SCHEMBL2171695

O=C(CCl)OCC(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7439614 0.81 ADRA2A (0.37) TSHRALDH1A1POLB
SCHEMBL9521455 0.81 MGAM (0.43) ALDH1A1POLB
SCHEMBL1693975 0.81 MAPK1 (0.37) TSHRALDH1A1
SCHEMBL10403259 0.79 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL10403258 0.79 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL6447039 0.77 NAAA (0.41) ALDH1A1POLB
SCHEMBL10105403 0.77 TSHR (0.40) TSHRALDH1A1POLB
SCHEMBL3082498 0.77 HTT (0.50) TSHRALDH1A1
SCHEMBL3042462 0.77 ALDH1A1 (0.31) ALDH1A1POLB
SCHEMBL2063825 0.77 ALDH1A1 (0.48) TSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023544-B Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method 中国石油化工股份有限公司 2024-12-06 CN claimed
CN-116023542-B Catalyst component, catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-09-17 CN claimed
CN-116023544-B Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method 中国石油化工股份有限公司 2024-12-06 CN disclosed
CN-116023542-B Catalyst component, catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-09-17 CN disclosed
EP-1964925-B1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES MITSUBISHI TANABE PHARMA CORP (JP) 2016-03-30 EP disclosed
US-7972836-B2 Method of enzymatic optical resolution of racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-07-05 US disclosed
US-20090269821-A1 Method for Preparing Optically Active 4-Hydroxy-1,2,3,4-Tetrahydroquinoline Compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2009-10-29 US disclosed
EP-1964925-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES Mitsubishi Tanabe Pharma Corporation (JP) 2008-09-03 EP disclosed
US-5252731-A Antibiotics FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-12 US disclosed
US-5110921-A Bactericides FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-05-05 US disclosed
US-4960889-A CEPHALOSPORIN INTERMEDIATES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-10-02 US disclosed
US-4731443-A 7-acylamino-3-vinylcephalosporanic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-03-15 US disclosed
US-4487927-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-11 US disclosed
US-4423213-A ANTIBIOTIC FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-12-27 US disclosed