Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508579 | 0.95 | DGKA (0.41) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL4078930 | 0.91 | ALDH1A1 (0.38) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL4069039 | 0.91 | TSHR (0.48) | TSHRCYP1A2ALDH1A1POLBPAM | |
| SCHEMBL7439614 | 0.90 | ADRA2A (0.37) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL8894297 | 0.89 | DGKA (0.33) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL3171515 | 0.89 | POLB (0.35) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL9095809 | 0.87 | DGKA (0.50) | TSHRDGKACYP1A2ALDH1A1PAM | |
| SCHEMBL26983152 | 0.87 | LMNA (0.46) | TSHRALDH1A1PAMLMNAMEN1 | |
| SCHEMBL3165640 | 0.87 | DGKA (0.36) | TSHRDGKACYP1A2ALDH1A1POLB | |
| SCHEMBL15561379 | 0.85 | GPR84 (0.41) | TSHRDGKAALDH1A1PAMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085479-A1 | PROCESS FOR PREPARING PLATINUM-CARBENE COMPLEXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085475-A1 | NOVEL PLATINUM-CARBENE COMPLEXES AND USE THEREOF AS MEDICAMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-06-28 | — | — | WO | disclosed |