Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653452 | 0.77 | L3MBTL1 (0.49) | L3MBTL1LMNAPKMHPGD | |
| SCHEMBL18364892 | 0.77 | MAPT (0.57) | L3MBTL1LMNAEPHX1ALDH1A1PPID | |
| SCHEMBL714625 | 0.77 | EPHX1 (0.77) | LMNAHPGDEPHX1ALDH1A1PPID | |
| SCHEMBL14451342 | 0.75 | ALDH1A1 (0.69) | L3MBTL1LMNAPKMHPGDUSP2 | |
| SCHEMBL5519093 | 0.75 | ALDH1A1 (0.69) | L3MBTL1LMNAPKMHPGDUSP2 | |
| SCHEMBL6666657 | 0.74 | FABP7 (0.58) | L3MBTL1LMNAPKMHPGDALDH1A1 | |
| SCHEMBL10917021 | 0.74 | FABP7 (0.58) | L3MBTL1LMNAPKMHPGDALDH1A1 | |
| SCHEMBL280126 | 0.74 | FABP7 (0.58) | L3MBTL1LMNAPKMHPGDALDH1A1 | |
| SCHEMBL2469546 | 0.74 | ALDH1A1 (0.86) | HPGDUSP2ALDH1A1MAPTMAPK1 | |
| SCHEMBL29675228 | 0.74 | ALDH1A1 (0.86) | HPGDUSP2ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346871-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | PRISM BioLab Corporation (JP) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010044485-A1 | ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER | PRISM BIOLAB CORPORATION (JP) | 2010-04-22 | — | — | WO | disclosed |