SCHEMBL4653452

SCHEMBL4653452

O=C(O)NCOC(=O)C1CCC(Cc2ccccc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
PKM P14618 2/20 0.49
LMNA P02545 1/20 0.49
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
FAAH O00519 3/20 0.43
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HTR2B P41595 2/20 0.41
MAPK14 Q16539 2/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654834 0.88 TAS2R14 (0.43) L3MBTL1PKMLMNAMEN1KMT2A
SCHEMBL4653433 0.88 MEN1 (0.56) LMNAMEN1KMT2AHPGD
SCHEMBL5523733 0.84 L3MBTL1 (0.59) L3MBTL1PKMLMNAMEN1KMT2A
SCHEMBL5523736 0.84 L3MBTL1 (0.59) L3MBTL1PKMLMNAMEN1KMT2A
SCHEMBL4654593 0.84 MAPK1 (0.48) L3MBTL1LMNAMEN1KMT2A
SCHEMBL13929453 0.81 ALDH1A1 (0.55) L3MBTL1LMNAMEN1KMT2AFAAH
SCHEMBL12404098 0.81 ALDH1A1 (0.55) L3MBTL1LMNAMEN1KMT2AFAAH
SCHEMBL2171698 0.77 L3MBTL1 (0.69) L3MBTL1PKMLMNAHPGD
SCHEMBL3515654 0.75 GBA1 (0.53) L3MBTL1LMNAMEN1KMT2AFAAH
SCHEMBL1662783 0.75 GBA1 (0.53) L3MBTL1LMNAMEN1KMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC L3MBTL1 3668/4885PKM 3215/4885LMNA 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.