SCHEMBL217175

SCHEMBL217175

CCc1ccccc1[C]1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALOX15 P16050 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
BCHE P06276 1/20 0.41
POLB P06746 1/20 0.41
PTPRC P08575 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41
HPGD P15428 1/20 0.41
PTPN1 P18031 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217631 0.85 LMNA (0.36) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL216310 0.85 SETD7 (0.36) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL2973991 0.82 NR1H2 (0.42) LMNAALOX15SETD7CYP2D6CYP1A2
SCHEMBL2970777 0.80 NR1H2 (0.48) PTPN1SETD7
SCHEMBL2974311 0.80 LMNA (0.36) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL2973222 0.80 LMNA (0.36) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL2960910 0.79 NR1H2 (0.50) THRBPTPN1SETD7
SCHEMBL2964831 0.79 NR1H2 (0.50) THRBPTPN1SETD7
SCHEMBL2964402 0.79 NR1H2 (0.50) THRBPTPN1SETD7
SCHEMBL2964256 0.79 NR1H2 (0.50) THRBPTPN1SETD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US disclosed
EP-0749985-B1 Stereo rigid metallocene compounds TICONA GMBH (DE) 2004-09-22 EP disclosed
EP-1175424-A1 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS Basell Polyolefine GmbH (DE) 2002-01-30 EP disclosed
WO-2000064906-A1 CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2000-11-02 WO disclosed
EP-1017730-A2 INJECTION MOULDING ARTICLES MADE OF METALLOCENE AND POLYPROPYLENE Basell Polyolefine GmbH (DE) 2000-07-12 EP disclosed
US-6063949-A Stereorigid metallocene compound TARGOR GMBH (DE) 2000-05-16 US disclosed
WO-1999011678-A2 INJECTION MOULDING ARTICLES MADE OF METALLOCENE AND POLYPROPYLENE TARGOR GMBH (DE) 1999-03-11 WO disclosed
EP-0749988-A2 Process for the preparation of cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-27 EP disclosed
EP-0749985-A2 Stereo rigid metallocene compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization PYM1, ZNF207, POLL LMNA 1336/4885MEN1 521/4885KMT2A 3037/4885
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 LMNA 755/4885MEN1 1786/4885KMT2A 3569/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 LMNA 4060/4885MEN1 2743/4885KMT2A 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.