SCHEMBL217631

SCHEMBL217631

CCc1cccc([C]2C=Cc3ccccc32)c1CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALOX15 P16050 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36
PTPRC P08575 1/20 0.36
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
IDO1 P14902 1/20 0.36
HPGD P15428 1/20 0.36
PTPN1 P18031 1/20 0.36
ACHE P22303 1/20 0.36
CES1 P23141 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217175 0.85 LMNA (0.41) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL216177 0.80 SETD7 (0.33) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL4529434 0.77 GABRA1 (0.50) LMNAGABRA1GABRB2CYP2D6MGLL
SCHEMBL473257 0.75 GABRA1 (0.44) LMNAMAPTALDH1A1GABRA1GABRB2
SCHEMBL216310 0.75 SETD7 (0.36) LMNAMEN1KMT2AALOX15MAPT
SCHEMBL217632 0.75 GABRA1 (0.34) GABRA1GABRB2CYP2D6HTR1APDK2
SCHEMBL2973991 0.72 NR1H2 (0.42) LMNAALOX15SETD7CYP2D6HTR1A
SCHEMBL473270 0.72 PDCD1 (0.50) KMT2AGABRA1GABRB2CYP2D6PDCD1
SCHEMBL2970777 0.71 NR1H2 (0.48) PTPN1SETD7
SCHEMBL11382363 0.71 PDCD1 (0.48) KMT2AGABRA1GABRB2CYP2D6PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
WO-2008140875-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-20 WO disclosed
US-20080287617-A1 Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2008-11-20 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 LMNA 2508/4885MEN1 1680/4885KMT2A 1057/4885
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 LMNA 3684/4885MEN1 2338/4885KMT2A 2995/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 LMNA 3055/4885MEN1 2914/4885KMT2A 2639/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 LMNA 4060/4885MEN1 2743/4885KMT2A 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.