Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6012074 | 0.82 | CA2 (0.60) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL453442 | 0.82 | CA2 (0.60) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10931933 | 0.82 | CA2 (0.60) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11461045 | 0.80 | CA2 (0.58) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6723769 | 0.79 | CA1 (0.64) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7644248 | 0.79 | BCAT1 (0.67) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL370189 | 0.78 | CA2 (0.56) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL209632 | 0.78 | DHFR (0.66) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10817093 | 0.78 | CA2 (0.56) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL209631 | 0.78 | CA2 (0.56) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973163-B2 | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| EP-1740584-B9 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-20090275568-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| US-20090270625-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090258893-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7592453-B2 | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-22 | — | — | US | disclosed |
| EP-2080760-A1 | Fused quinoline derivative and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-1740584-B1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-20080039452-A1 | Fused Quinoline Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1740584-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-5567578-A | HIGH FASTNESS TO LIGHT ALL FROM THE HIGH-DENSITY AREAS TO THE LOW-DENSITY AREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| US-5496693-A | YELLOW COLOR-FORMING SILVER HALIDE EMULSION LAYER FORMED ON A SUPPORT AND CONTAINING YELLOW COLOR-FORMING COUPLER DISPERSED BY DISSOLUTION IN HIGH-BOILING ORGANIC PHOSPHORUS-OXYGEN SOLVENT, COUPLER BEING A DERIVATIVE OF MALONIC ACID DIAMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5462845-A | Having reflective support surface coated with white pigment dispersed in polyester, containing specifed yellow dye-forming coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0557851-B1 | Method for processing color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5427896-A | Containing an oil soluble cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5409807-A | Yellow color forming silver halide emulsion layer formed on a support, contains yellow color forming coupler dispersed by dissolution of high boiling solvent | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5374507-A | Containing specific yellow dye-forming coupler, hydrophilic colloid layer with white pigment | FUJI PHOTO FILM CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0578249-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |
| EP-0573761-A1 | Method of forming coloured images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0557851-A1 | Method for processing color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275568-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TACR2, HRH3, HRH2 | CA2 829/4885CA1 2912/4885MMP1 4782/4885 |
| US-20090258893-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TACR2, HRH3, HRH2 | CA2 829/4885CA1 2912/4885MMP1 4782/4885 |
| US-20080039452-A1 | Fused Quinoline Derivative and Use Thereof | TACR2, HRH3, HRH2 | CA2 859/4885CA1 2923/4885MMP1 4779/4885 |
| US-20090270625-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TACR2, HRH3, HRH2 | CA2 777/4885CA1 2906/4885MMP1 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.