Sugi Predict

Sugi Predict / Compounds / SCHEMBL21723905

SCHEMBL21723905

SCHEMBL21723905

CCN(CC)c1ccc(-c2cc3c(s2)c(-c2ccc(C#N)cc2)cc(=O)n3C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.39
▸ BRD1 O95696 1/20 0.36
▸ BRPF1 P55201 1/20 0.36
▸ MCHR1 Q99705 2/20 0.35
▸ PRKDC P78527 1/20 0.34
▸ CREBBP Q92793 1/20 0.34
▸ MEN1 O00255 3/20 0.33
▸ MAPT P10636 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ CYP11B2 P19099 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ STK17B O94768 1/20 0.33
▸ MAP3K8 P41279 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21723978 0.87 HSD17B10 (0.44) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL27217472 0.86 ESR1 (0.35) MCHR1MEN1MAPTKMT2AKDM4E
SCHEMBL21723952 0.84 GSK3B (0.41) MCHR1MEN1MAPTKMT2AKDM4E
SCHEMBL21723927 0.83 RARB (0.44) MEN1MAPTKMT2AALDH1A1HPGD
SCHEMBL21723934 0.82 NPC1 (0.42) BRD1BRPF1MCHR1MAPTKDM4E
SCHEMBL21723837 0.81 MAPT (0.36) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL21723957 0.80 BACE1 (0.39) PGRMCHR1MEN1MAPTKMT2A
SCHEMBL21723917 0.80 ALDH1A1 (0.38) MCHR1MEN1MAPTKMT2AKDM4E
SCHEMBL21723630 0.78 GSK3B (0.38) MCHR1CREBBPMEN1MAPTKMT2A
SCHEMBL23451965 0.76 ALDH1A1 (0.38) MEN1MAPTKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) 2025-09-16 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
WO-2020036243-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR 한국해양과학기술원 2020-02-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR FARS2, CYP4F11, CYP4B1 PGR 1582/4885BRD1 1144/4885BRPF1 669/4885
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor FARS2, CYP4F11, CYP4B1 PGR 1582/4885BRD1 1144/4885BRPF1 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.