Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723987 | 0.89 | NPC1 (0.48) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL21723978 | 0.88 | HSD17B10 (0.44) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL27217472 | 0.87 | ESR1 (0.35) | GSK3BNPC1RAB9AKDM4EMAPT | |
| SCHEMBL21723837 | 0.86 | MAPT (0.36) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL21723639 | 0.84 | HSD17B10 (0.47) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL21723927 | 0.84 | RARB (0.44) | NPC1RAB9APKMMAPTMAPK1 | |
| SCHEMBL21723905 | 0.84 | PGR (0.39) | KDM4EMAPTMAPK1MEN1KMT2A | |
| SCHEMBL27217475 | 0.81 | NPC1 (0.39) | GSK3BNPC1RAB9AKDM4EPKM | |
| SCHEMBL21723957 | 0.81 | BACE1 (0.39) | NPC1RAB9AKDM4EPKMMAPT | |
| SCHEMBL21723917 | 0.81 | ALDH1A1 (0.38) | GSK3BNPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158693-A1 | Probe for Hydrogen Sulfide Detection, Method for Manufacturing Same, and Composition for Hydrogen Sulfide Detection, Comprising Same | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2024-05-16 | — | — | US | claimed |
| WO-2022131557-A1 | PROBE FOR HYDROGEN SULFIDE DETECTION, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR HYDROGEN SULFIDE DETECTION, COMPRISING SAME | 한국해양과학기술원 | 2022-06-23 | — | — | WO | claimed |
| US-12415813-B2 | Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2025-09-16 | — | — | US | disclosed |
| US-20240158693-A1 | Probe for Hydrogen Sulfide Detection, Method for Manufacturing Same, and Composition for Hydrogen Sulfide Detection, Comprising Same | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2024-05-16 | — | — | US | disclosed |
| WO-2022131557-A1 | PROBE FOR HYDROGEN SULFIDE DETECTION, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR HYDROGEN SULFIDE DETECTION, COMPRISING SAME | 한국해양과학기술원 | 2022-06-23 | — | — | WO | disclosed |
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) | 2021-10-28 | — | — | US | disclosed |
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) | 2021-10-28 | — | — | US | disclosed |
| WO-2020036243-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | 한국해양과학기술원 | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | FARS2, CYP4F11, CYP4B1 | GSK3B 3057/4885NPC1 3352/4885RAB9A 3000/4885 |
| US-12415813-B2 | Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor | FARS2, CYP4F11, CYP4B1 | GSK3B 3057/4885NPC1 3352/4885RAB9A 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.