Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.44 |
| ▸ | RARG | P13631 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723978 | 0.89 | HSD17B10 (0.44) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL21723837 | 0.89 | MAPT (0.36) | RARBRARGMAPTALDH1A1MAPK1 | |
| SCHEMBL27217472 | 0.88 | ESR1 (0.35) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL23451965 | 0.85 | ALDH1A1 (0.38) | RARBRARGMAPTALDH1A1MAPK1 | |
| SCHEMBL21723952 | 0.84 | GSK3B (0.41) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL21723905 | 0.83 | PGR (0.39) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL21723957 | 0.80 | BACE1 (0.39) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL21723917 | 0.80 | ALDH1A1 (0.38) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL23452121 | 0.78 | MAPT (0.37) | MAPTALDH1A1MAPK1HPGDL3MBTL1 | |
| SCHEMBL21723630 | 0.78 | GSK3B (0.38) | MAPTALDH1A1MAPK1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036243-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | 한국해양과학기술원 | 2020-02-20 | — | — | WO | disclosed |