Sugi Predict

Sugi Predict / Compounds / SCHEMBL21723978

SCHEMBL21723978

SCHEMBL21723978

CCN(CC)c1ccc(-c2cc3c(s2)c(-c2ccccc2)cc(=O)n3C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.44
▸ RAB9A P51151 5/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ GAA P10253 1/20 0.38
▸ PDE7A Q13946 1/20 0.37
▸ ADORA2A P29274 1/20 0.36
▸ ALDH1A1 P00352 6/20 0.36
▸ MAPT P10636 5/20 0.36
▸ HPGD P15428 3/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ NPC1 O15118 4/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ USP2 O75604 1/20 0.35
▸ CTNNB1 P35222 1/20 0.35
▸ ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27217472 0.90 ESR1 (0.35) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723927 0.89 RARB (0.44) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723952 0.88 GSK3B (0.41) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723905 0.87 PGR (0.39) HSD17B10MEN1KMT2AGAAALDH1A1
SCHEMBL21723957 0.86 BACE1 (0.39) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723630 0.85 GSK3B (0.38) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723837 0.84 MAPT (0.36) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL21723917 0.83 ALDH1A1 (0.38) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL25832640 0.83 GRIA2 (0.41) HSD17B10RAB9AMEN1KMT2AGAA
SCHEMBL25258407 0.82 GRIA2 (0.41) HSD17B10RAB9AMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) 2025-09-16 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
WO-2020036243-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR 한국해양과학기술원 2020-02-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR FARS2, CYP4F11, CYP4B1 HSD17B10 2367/4885RAB9A 3000/4885MEN1 1767/4885
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor FARS2, CYP4F11, CYP4B1 HSD17B10 2367/4885RAB9A 3000/4885MEN1 1767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.