Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723951 | 0.86 | PYCR1 (0.48) | PYCR1RIPK1TAAR1BCHENPC1 | |
| SCHEMBL21723776 | 0.86 | — | — | |
| SCHEMBL21723933 | 0.84 | MEN1 (0.46) | RIPK1TAAR1NPC1 | |
| SCHEMBL21723914 | 0.83 | PYCR1 (0.41) | PYCR1TAAR1MAPTNPC1 | |
| SCHEMBL10852766 | 0.83 | RAB9A (0.46) | SIGMAR1MAPTNPC1 | |
| SCHEMBL21724485 | 0.82 | SMN1; SMN2 (0.47) | TP53MAPTBCHE | |
| SCHEMBL21723766 | 0.81 | ALDH1A1 (0.43) | MAPT | |
| SCHEMBL21723955 | 0.81 | MEP1A (0.44) | — | |
| SCHEMBL21724766 | 0.80 | TACR1 (0.38) | NPC1 | |
| SCHEMBL21723910 | 0.80 | PYCR1 (0.52) | PYCR1SIGMAR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |