Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723951 | 0.86 | PYCR1 (0.48) | RIPK1TAAR1ALDH1A1NPC1 | |
| SCHEMBL21724535 | 0.84 | PYCR1 (0.46) | RIPK1TAAR1NPC1 | |
| SCHEMBL21723766 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL21724804 | 0.83 | DAO (0.43) | RIPK1TAAR1ALDH1A1NPC1TDP1 | |
| SCHEMBL10852766 | 0.83 | RAB9A (0.46) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL21724485 | 0.82 | SMN1; SMN2 (0.47) | MEN1KMT2AGRIN1ALDH1A1HPGD | |
| SCHEMBL21723955 | 0.81 | MEP1A (0.44) | MEN1KMT2ASLC6A3HSD17B1HSD17B2 | |
| SCHEMBL21724598 | 0.80 | CETP (0.44) | CHRM2CHRM3 | |
| SCHEMBL21723910 | 0.80 | PYCR1 (0.52) | ALDH1A1NPC1KDM4ETDP1 | |
| SCHEMBL21724519 | 0.79 | GAA (0.41) | MEN1KMT2ATAAR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |