Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723873 | 0.86 | TACR1 (0.44) | — | |
| SCHEMBL21723766 | 0.84 | ALDH1A1 (0.43) | KDM4EGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL21724804 | 0.84 | DAO (0.43) | PYCR1KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL21723900 | 0.84 | PDE2A (0.42) | PYCR1LSSLMNAKDM4EGAA | |
| SCHEMBL21723901 | 0.83 | PTPRZ1 (0.38) | LMNAKDM4EGAANPSR1FABP4 | |
| SCHEMBL21724517 | 0.83 | LSS (0.42) | LSSMEN1KMT2AALDH1A1 | |
| SCHEMBL21724331 | 0.82 | PYCR1 (0.39) | PYCR1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL21723969 | 0.81 | ALDH1A1 (0.39) | KDM4EHTTMEN1KMT2ACNR1 | |
| SCHEMBL21723914 | 0.81 | PYCR1 (0.41) | PYCR1LSSLMNAKDM4EGAA | |
| SCHEMBL21723975 | 0.81 | NPC1 (0.36) | HTTSMN1; SMN2NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |