Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724539 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHDAC1KDM4E | |
| SCHEMBL21723632 | 0.89 | HDAC1 (0.42) | SMN1; SMN2LMNAHDAC1HRH3KDM4E | |
| SCHEMBL21723648 | 0.84 | ALDH1A1 (0.48) | SMN1; SMN2 | |
| SCHEMBL21724014 | 0.81 | POLB (0.42) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL21724517 | 0.80 | LSS (0.42) | — | |
| SCHEMBL21724331 | 0.79 | PYCR1 (0.39) | SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL21723902 | 0.78 | MTOR (0.38) | — | |
| SCHEMBL21723969 | 0.78 | ALDH1A1 (0.39) | HDAC1KDM4EHDAC6 | |
| SCHEMBL21724804 | 0.78 | DAO (0.43) | SMN1; SMN2LMNAPKM | |
| SCHEMBL21723914 | 0.78 | PYCR1 (0.41) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |