Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723648 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NPSR1KMT2AMEN1 | |
| SCHEMBL21723672 | 0.83 | PYCR1 (0.44) | LMNACNR2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21724539 | 0.83 | SMN1; SMN2 (0.51) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL21724517 | 0.81 | LSS (0.42) | CNR2ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL21723970 | 0.81 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2KDM4E | |
| SCHEMBL21724331 | 0.80 | PYCR1 (0.39) | TSPOLMNAL3MBTL1CNR2MAPT | |
| SCHEMBL21723902 | 0.79 | MTOR (0.38) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL21723969 | 0.79 | ALDH1A1 (0.39) | POLBCNR2MAPTALDH1A1TP53 | |
| SCHEMBL21723914 | 0.79 | PYCR1 (0.41) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL21724804 | 0.79 | DAO (0.43) | KCNH2LMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |