Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723609 | 0.84 | KMT2A (0.43) | MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL21724768 | 0.83 | PYCR1 (0.44) | NPSR1FABP4KDM4EALDH1A1LMNA | |
| SCHEMBL21724804 | 0.81 | DAO (0.43) | MAPTNPSR1ALDH1A1TDP1LMNA | |
| SCHEMBL21724517 | 0.80 | LSS (0.42) | EPHX2NR1H4ALDH1A1NPC1 | |
| SCHEMBL21724331 | 0.79 | PYCR1 (0.39) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL21723914 | 0.78 | PYCR1 (0.41) | MAPTKDM4EALDH1A1TDP1LMNA | |
| SCHEMBL21723969 | 0.78 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1TDP1POLB | |
| SCHEMBL21723902 | 0.78 | MTOR (0.38) | ALDH1A1CA2CA9NPC1RAB9A | |
| SCHEMBL10852766 | 0.78 | RAB9A (0.46) | MAPTKDM4EALDH1A1CA9NPC1 | |
| SCHEMBL21723672 | 0.77 | PYCR1 (0.44) | KDM4EALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |