Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 5/20 | 0.42 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12219908 | 0.86 | CHEK1 (0.53) | KDM4EKIF11RNASEH1DAOEIF4A3 | |
| SCHEMBL13850171 | 0.86 | DAO (0.53) | KDM4EKIF11HSD17B10RNASEH1DAO | |
| SCHEMBL12219900 | 0.77 | TBK1 (0.40) | KDM4EKIF11RNASEH1EIF4A3PTPN1 | |
| SCHEMBL12219897 | 0.76 | PARP1 (0.39) | KDM4EKIF11RNASEH1EIF4A3PTPN1 | |
| SCHEMBL8164001 | 0.76 | MCL1 (0.40) | KDM4EKIF11RNASEH1EIF4A3PTPN1 | |
| SCHEMBL13361459 | 0.76 | RNASEH1 (0.39) | KDM4EKIF11RNASEH1EIF4A3PTPN1 | |
| SCHEMBL8161177 | 0.76 | HTR1D (0.41) | KDM4EKIF11RNASEH1DAOEIF4A3 | |
| SCHEMBL20982388 | 0.76 | PTPN1 (0.45) | KDM4EKIF11RNASEH1EIF4A3PTPN1 | |
| SCHEMBL8184390 | 0.75 | HTR1D (0.47) | KDM4EKIF11RNASEH1TBK1AURKA | |
| SCHEMBL18363786 | 0.74 | KIF11 (0.38) | KDM4EKIF11RNASEH1DAOEIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | KDM4E 2957/4885KIF11 1469/4885HSD17B10 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.