Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307596 | 0.79 | CCR2 (0.44) | KMT2ACCR2CYP17A1NPC1RAB9A | |
| SCHEMBL21731428 | 0.79 | KDM4E (0.43) | KMT2AALDH1A1GAA | |
| SCHEMBL14076727 | 0.78 | CCR2 (0.41) | KMT2ACCR2CYP17A1NPC1RAB9A | |
| SCHEMBL21731373 | 0.78 | GAA (0.43) | KMT2AALDH1A1GAA | |
| SCHEMBL465792 | 0.78 | CCR2 (0.42) | KMT2ACCR2CYP17A1NPC1RAB9A | |
| SCHEMBL30396325 | 0.78 | CCR2 (0.42) | KMT2ACCR2CYP17A1NPC1RAB9A | |
| SCHEMBL4076010 | 0.78 | CHRNB2 (0.51) | CCR2CYP17A1MAPKAPK2SYKLCK | |
| SCHEMBL17617912 | 0.77 | SMN1; SMN2 (0.46) | CCR2CYP17A1LCKSCN9APTGER1 | |
| SCHEMBL21198393 | 0.76 | CCR2 (0.42) | KMT2ACCR2CYP17A1MAPKAPK2NPC1 | |
| SCHEMBL1022260 | 0.76 | GLS (0.42) | KMT2ACCR2CYP17A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |