Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166137 | 0.79 | MAPT (0.34) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL6267324 | 0.77 | NOS1 (0.37) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL24884220 | 0.74 | NOS1 (0.35) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL20743690 | 0.74 | PTGS2 (0.32) | RIPK2 | |
| SCHEMBL24737152 | 0.70 | NOS1 (0.41) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL24813878 | 0.70 | MAPT (0.36) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL12436779 | 0.69 | LMNA (0.40) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL22305675 | 0.69 | CYP4F2 (0.35) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL6904862 | 0.67 | MAPT (0.38) | HTTALDH1A1USP2ALOX15NPSR1 | |
| SCHEMBL22679520 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035465-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |