Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.35 |
| ▸ | ADH1A | P07327 | 3/20 | 0.35 |
| ▸ | ADH7 | P40394 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084865 | 0.80 | ADH1B (0.39) | ADH1BADH1AADH7PKMADH1C | |
| SCHEMBL12572077 | 0.79 | ADH1B (0.33) | ADH1BADH1AADH7PKMADH1C | |
| SCHEMBL15431831 | 0.79 | POLB (0.35) | PKMPOLBGAANPSR1 | |
| SCHEMBL36866 | 0.77 | POLB (0.41) | POLBGAANPSR1 | |
| SCHEMBL18844763 | 0.77 | POLB (0.34) | POLBGAANPSR1 | |
| SCHEMBL4323160 | 0.77 | ALDH1A1 (0.34) | ADH1BADH1AADH7ADH1CPOLB | |
| SCHEMBL26785160 | 0.76 | CTSK (0.32) | — | |
| SCHEMBL15965828 | 0.76 | MTNR1A (0.43) | GAA | |
| SCHEMBL5652323 | 0.74 | — | — | |
| SCHEMBL16661383 | 0.74 | POLB (0.30) | POLBGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3254678-B1 | MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2020-02-19 | — | — | EP | disclosed |