Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL7770892 | 0.86 | ADORA1 (0.37) | ADORA1ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL28320162 | 0.85 | HTR6 (0.38) | ADORA1ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL28320167 | 0.84 | MPO (0.43) | ADORA1ADORA2AADORA2BADORA3TAAR1 | |
| SCHEMBL288235 | 0.84 | ADORA1 (0.51) | ADORA1ADORA2AADORA2BCYP1A2CYP3A4 | |
| SCHEMBL448638 | 0.84 | CDC7 (0.37) | ADORA1ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL1422153 | 0.82 | ALDH1A1 (0.47) | ADORA1CYP2D6 | |
| SCHEMBL15300300 | 0.82 | MPO (0.41) | ADORA1ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL16146156 | 0.82 | PDE4A (0.47) | ADORA1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16147020 | 0.82 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| SCHEMBL16147209 | 0.81 | PDE4A (0.52) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3062619-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2019-07-24 | — | — | EP | claimed |
| US-9909169-B2 | Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2018-03-06 | — | — | US | claimed |
| EP-2934135-B1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-01-31 | — | — | EP | claimed |
| EP-3234180-A1 | ALLELE-SPECIFIC AMPLIFICATION OF NUCLEIC ACIDS USING BLOCKING OLIGONUCLEOTIDES FOR WILD TYPE SUPPRESSION | Roche Diagnostics GmbH (DE) | 2017-10-25 | — | — | EP | claimed |
| EP-2931917-B1 | PRIMERS WITH MODIFIED PHOSPHATE AND BASE IN ALLELE-SPECIFIC PCR | ROCHE DIAGNOSTICS GMBH (DE) | 2017-04-05 | — | — | EP | claimed |
| WO-2016096814-A1 | ALLELE-SPECIFIC AMPLIFICATION OF NUCLEIC ACIDS USING BLOCKING OLIGONUCLEOTIDES FOR WILD TYPE SUPPRESSION | ROCHE DIAGNOSTICS GMBH (DE) | 2016-06-23 | — | — | WO | claimed |
| US-20160177372-A1 | ALLELE-SPECIFIC AMPLIFICATION OF NUCLEIC ACIDS USING BLOCKING OLIGONUCLEOTIDES FOR WILD TYPE SUPPRESSION | ROCHE MOLECULAR SYSTEMS, INC. | 2016-06-23 | — | — | US | claimed |
| US-9238832-B2 | Allele-specific amplification of nucleic acids | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2016-01-19 | — | — | US | claimed |
| EP-2931917-A1 | PRIMERS WITH MODIFIED PHOSPHATE AND BASE IN ALLELE-SPECIFIC PCR | Roche Diagnostics GmbH (DE) | 2015-10-21 | — | — | EP | claimed |
| CN-104447746-A | Compound for activating AMPK and application thereof | HUAAN MEDICAL CO LTD | 2015-03-25 | — | — | CN | claimed |
| WO-2011069677-A1 | ALLELE-SPECIFIC AMPLIFICATION OF NUCLEIC ACIDS | ROCHE DIAGNOSTICS GMBH (DE) | 2011-06-16 | — | — | WO | claimed |
| WO-2010046067-A9 | IMPROVED ALLELE-SPECIFIC AMPLIFICATION | ROCHE DIAGNOSTICS GMBH (DE) | 2010-07-15 | — | — | WO | claimed |
| WO-2010046067-A1 | IMPROVED ALLELE-SPECIFIC AMPLIFICATION | ROCHE DIAGNOSTICS GMBH (DE) | 2010-04-29 | — | — | WO | claimed |
| US-20100099110-A1 | Allele-Specific Amplification | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-04-22 | — | — | US | claimed |
| CN-100459850-C | Method for saussurea involucrate callus induction and tissue culture sprout quick reproduction | INST PROCESS ENG CAS (CN) | 2009-02-11 | — | — | CN | claimed |
| CN-1907013-A | Method for saussurea involucrate callus induction and tissue culture sprout quick reproduction | INST PROCESS ENG CAS (CN) | 2007-02-07 | — | — | CN | claimed |
| US-6677154-B2 | PREPARTION OF GROWTH NUTRIENT FOR PLANTS; OBTAIN PLANT, REMOVE STEMS, PROPAGATE IN TISSUE CULTURE | GIELIS JOHAN (BE) | 2004-01-13 | — | — | US | claimed |
| US-20020086425-A1 | MICROPROPAGATION, SYNTHETIC SEEDS AND GERMPLASM STORAGE OF BAMBOOS | GIELIS JOHAN (BE) | 2002-07-04 | — | — | US | claimed |
| WO-2000053727-A1 | MICROPROPAGATION, SYNTHETIC SEEDS AND GERMPLASM STORAGE OF BAMBOOS | GIELIS JOHAN (BE) | 2000-09-14 | — | — | WO | claimed |
| US-5821126-A | TRUE-TO-TYPE SUSPENSOR DEVELOPMENT OF CONIFER EMBROY LEADING TO DEVELOPMENT OF PLANTLETS AND PLANTS; GENETIC ENGINEERING; CULTURING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-10-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099110-A1 | Allele-Specific Amplification | RNGTT, HLA-C, POLL | ADORA1 520/4885ADORA2A 354/4885ADORA2B 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.