SCHEMBL21734291

SCHEMBL21734291

CC(C)C1C2CCC1c1c(I)cccc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.33
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220702 0.79 PNMT (0.35) SIGMAR1PNMT
SCHEMBL15800482 0.79 PNMT (0.35) SIGMAR1PNMT
SCHEMBL2496114 0.79 SIGMAR1 (0.38) SIGMAR1PNMT
SCHEMBL12023267 0.79 PNMT (0.35) SIGMAR1PNMT
SCHEMBL14335852 0.77 SIGMAR1 (0.42) SIGMAR1
SCHEMBL13226814 0.69 SIGMAR1 (0.39) SIGMAR1
SCHEMBL4690809 0.66 CA2 (0.31)
SCHEMBL22932064 0.61 DRD2 (0.31)
SCHEMBL15222367 0.61
SCHEMBL16953574 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034181-A9 QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 中国农业大学 2020-08-13 WO disclosed
WO-2020034181-A1 QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 中国农业大学 2020-02-20 WO disclosed