Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735166 | 0.85 | — | — | |
| SCHEMBL21735168 | 0.84 | PPARG (0.32) | CNR2 | |
| SCHEMBL21735813 | 0.84 | MTNR1A (0.42) | MTNR1AMTNR1BPSEN1PSEN2APH1B | |
| SCHEMBL21735173 | 0.83 | ALDH1A1 (0.32) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21735148 | 0.80 | — | — | |
| SCHEMBL21735134 | 0.79 | — | — | |
| SCHEMBL22629901 | 0.78 | — | — | |
| SCHEMBL21735156 | 0.76 | KMT2A (0.34) | MTNR1AMTNR1BALDH1A1KMT2A | |
| SCHEMBL22628843 | 0.76 | HDAC6 (0.36) | ALDH1A1MEN1GLAKMT2A | |
| SCHEMBL26292388 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1BPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885PSEN1 1388/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885PSEN1 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.