Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735347 | 0.88 | MTNR1A (0.38) | KMT2AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL21735689 | 0.81 | KMT2A (0.40) | KMT2AMTNR1AMTNR1BSMN1; SMN2NR1H2 | |
| SCHEMBL21735024 | 0.78 | CYP11B1 (0.35) | ALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL21735507 | 0.77 | NR1H2 (0.41) | KMT2AALDH1A1HPGDKDM4ENR1H2 | |
| SCHEMBL21735021 | 0.76 | MTNR1A (0.36) | KMT2AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL22630110 | 0.76 | MTNR1A (0.44) | KMT2AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL21735544 | 0.76 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21735702 | 0.75 | THRB (0.41) | KMT2AMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL21735701 | 0.75 | KMT2A (0.42) | KMT2AMTNR1AMTNR1BACSS2ALDH1A1 | |
| SCHEMBL21735699 | 0.74 | KMT2A (0.41) | KMT2AMTNR1AMTNR1BACSS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | KMT2A 4264/4885MTNR1A 3327/4885MTNR1B 2622/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | KMT2A 4264/4885MTNR1A 3327/4885MTNR1B 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.