Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | NDUFS8 | O00217 | 2/20 | 0.31 |
| ▸ | COXFA4 | O00483 | 2/20 | 0.31 |
| ▸ | NDUFAB1 | O14561 | 2/20 | 0.31 |
| ▸ | NDUFA1 | O15239 | 2/20 | 0.31 |
| ▸ | NDUFS4 | O43181 | 2/20 | 0.31 |
| ▸ | NDUFB5 | O43674 | 2/20 | 0.31 |
| ▸ | NDUFB3 | O43676 | 2/20 | 0.31 |
| ▸ | NDUFC1 | O43677 | 2/20 | 0.31 |
| ▸ | NDUFA2 | O43678 | 2/20 | 0.31 |
| ▸ | NDUFS5 | O43920 | 2/20 | 0.31 |
| ▸ | NDUFS7 | O75251 | 2/20 | 0.31 |
| ▸ | NDUFS2 | O75306 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735731 | 0.92 | S1PR1 (0.38) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL22625007 | 0.91 | MAOB (0.37) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL21735273 | 0.91 | S1PR1 (0.43) | S1PR1S1PR3MAOBMAOAPTGES | |
| SCHEMBL21735754 | 0.91 | S1PR1 (0.38) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL21735212 | 0.90 | S1PR1 (0.39) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL21735729 | 0.90 | THRB (0.40) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL25848597 | 0.87 | MAOB (0.36) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL21735750 | 0.86 | RAB9A (0.35) | S1PR1S1PR3MAOBMAOA | |
| SCHEMBL26291450 | 0.86 | S1PR1 (0.43) | S1PR1S1PR3SLC10A1MAOBMAOA | |
| SCHEMBL22625108 | 0.85 | MAOB (0.36) | S1PR1S1PR3SLC10A1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | S1PR1 3951/4885S1PR3 2314/4885SLC10A1 4684/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | S1PR1 3951/4885S1PR3 2314/4885SLC10A1 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.