Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735175 | 0.91 | POLB (0.37) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL21735177 | 0.91 | POLB (0.39) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL21735569 | 0.87 | POLB (0.40) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL22245884 | 0.86 | MTNR1A (0.42) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL21735546 | 0.85 | ACSS2 (0.47) | MTNR1AMTNR1BGRIK1GRIK2ACSS2 | |
| SCHEMBL22630104 | 0.84 | GRIK2 (0.50) | MTNR1AMTNR1BTDP1GRIK1GRIK2 | |
| SCHEMBL21735164 | 0.82 | POLB (0.35) | POLBAPEX1HTTTDP1ACSS2 | |
| SCHEMBL21735703 | 0.82 | MTNR1A (0.46) | MTNR1AMTNR1BMCL1L3MBTL1BACE1 | |
| SCHEMBL21735823 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BGRIK1GRIK2ACSS2 | |
| SCHEMBL21735513 | 0.81 | NR1H2 (0.45) | POLBAPEX1HTTTDP1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885POLB 3540/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885POLB 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.