SCHEMBL21736833

SCHEMBL21736833

CCc1ncc(N2CCCC2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 9/20 0.46
CHRNA4 P43681 9/20 0.46
IP6K1 Q92551 1/20 0.38
KDM4E B2RXH2 2/20 0.38
THRB P10828 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
CHRNA1 P02708 1/20 0.36
CHRNA7 P36544 1/20 0.36
TP53 P04637 2/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24595121 0.98 CHRNB2 (0.45) CHRNB2CHRNA4IP6K1KDM4ETHRB
SCHEMBL20389156 0.78 CHRNB2 (0.39) CHRNB2CHRNA4KDM4EHRH4
SCHEMBL21718816 0.73 CHRNB2 (0.46) CHRNB2CHRNA4IP6K1KDM4ELMNA
SCHEMBL24424942 0.73 HTR3A (0.46) CHRNB2CHRNA4KDM4ELMNAHRH4
SCHEMBL7193385 0.72 CHRNB2 (0.72) CHRNB2CHRNA4IP6K1KDM4EMAPT
SCHEMBL21718974 0.72 CHRNB2 (0.45) CHRNB2CHRNA4IP6K1KDM4ELMNA
SCHEMBL21736869 0.72 CHRNB2 (0.45) CHRNB2CHRNA4IP6K1KDM4ELMNA
SCHEMBL24611918 0.70 MAPT (0.45) CHRNB2CHRNA4LMNATSHRHTT
SCHEMBL10264617 0.70 CRHR1 (0.46) LMNATSHRHTTSMN1; SMN2
SCHEMBL21736792 0.69 L3MBTL1 (0.49) THRBLMNAHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed