Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780850 | 0.81 | SMN1; SMN2 (0.41) | ADRA2AADRA2BLMNACYP1A2HTR1A | |
| SCHEMBL21718436 | 0.79 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL361815 | 0.79 | TSHR (0.47) | ADRA2AADRA2BADRA2CHTR1AMAPK1 | |
| SCHEMBL21736868 | 0.78 | LMNA (0.43) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL17329279 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL3435213 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL21736935 | 0.78 | AR (0.44) | MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21736890 | 0.77 | ADRB2 (0.43) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL21736937 | 0.77 | ADRB2 (0.43) | ADRA2AADRA2BADRA2CADRB2ADRB1 | |
| SCHEMBL3699913 | 0.76 | IMPDH2 (0.49) | SMN1; SMN2ALDH1A1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |