Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175100 | 0.85 | PTGS2 (0.46) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL7109537 | 0.83 | HSD17B10 (0.46) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| Acetone SCHEMBL2176182 | 0.83 | LMNA (0.41) | HSD17B10KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL3259181 | 0.83 | PTGS2 (0.45) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL23567079 | 0.81 | ALDH1A1 (0.41) | HSD17B10KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL5012212 | 0.81 | TDP1 (0.41) | HSD17B10KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL6938579 | 0.81 | TDP1 (0.41) | HSD17B10KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL28347679 | 0.81 | PTGS2 (0.56) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL5035198 | 0.80 | TSHR (0.39) | KDM4EHPGDALDH1A1TSHRKMT2A | |
| SCHEMBL10873868 | 0.80 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250844-A1 | FORMULATIONS FROM NATURAL PRODUCTS, TURMERIC, PACLITAXEL, AND ASPIRIN | ORGANOMED CORPORATION | 2015-09-10 | — | — | US | disclosed |
| US-9012411-B2 | Formulations from derivatives of curcumin, paclitaxel, and aspirin | ORGANOMED CORPORATION (US) | 2015-04-21 | — | — | US | disclosed |
| US-20130029922-A1 | FORMULATIONS FROM NATURAL PRODUCTS, TURMERIC, PACLITAXEL, AND ASPIRIN | ORGANOMED CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2011082290-A2 | FORMULATIONS FROM NATURAL PRODUCTS, TURMERIC, AND ASPIRIN | ORGANOMED CORPORATION (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250844-A1 | FORMULATIONS FROM NATURAL PRODUCTS, TURMERIC, PACLITAXEL, AND ASPIRIN | PTGES, PTGES2, PTGES3 | PTGS2 9/4885HSD17B10 4076/4885KDM4E 4808/4885 |
| US-20130029922-A1 | FORMULATIONS FROM NATURAL PRODUCTS, TURMERIC, PACLITAXEL, AND ASPIRIN | PTGES, PTGES2, PTGES3 | PTGS2 9/4885HSD17B10 4076/4885KDM4E 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.