Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742869 | 1.00 | HPGD (0.38) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21742871 | 0.88 | PDK2 (0.38) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21742875 | 0.88 | PDK2 (0.38) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17191631 | 0.88 | MAPT (0.44) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21742872 | 0.87 | ALOX5 (0.49) | HPGDRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24571012 | 0.86 | PLA2G2A (0.43) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13443698 | 0.86 | AHR (0.42) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16491685 | 0.86 | NPC1 (0.36) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21742873 | 0.86 | MAOA (0.39) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21742673 | 0.85 | PDK2 (0.41) | HPGDRAB9ASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | HPGD 1884/4885RAB9A 2572/4885SMN1; SMN2 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.