Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742678 | 1.00 | PDK2 (0.36) | PDK2SLC9A1ALOX5GPR3ALDH1A1 | |
| SCHEMBL18086216 | 0.88 | GPR3 (0.42) | PDK2ALOX5GPR3ALDH1A1MAPT | |
| SCHEMBL21742531 | 0.87 | ALOX5 (0.49) | PDK2SLC9A1ALOX5ALDH1A1MAPT | |
| SCHEMBL21742801 | 0.87 | ALOX5 (0.49) | PDK2SLC9A1ALOX5ALDH1A1MAPT | |
| SCHEMBL13443699 | 0.86 | GPR3 (0.41) | PDK2ALOX5GPR3ALDH1A1MAPT | |
| SCHEMBL21742802 | 0.86 | SLC9A1 (0.36) | PDK2SLC9A1ALOX5GPR3ALDH1A1 | |
| SCHEMBL21742803 | 0.85 | PDK2 (0.41) | PDK2ALOX5GPR3ALDH1A1MAPT | |
| SCHEMBL21742677 | 0.85 | PDK2 (0.41) | PDK2ALOX5GPR3ALDH1A1MAPT | |
| SCHEMBL22930673 | 0.84 | ALDH1A1 (0.39) | PDK2SLC9A1ALOX5GPR3ALDH1A1 | |
| SCHEMBL22930625 | 0.84 | ALDH1A1 (0.37) | PDK2SLC9A1ALOX5GPR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | PDK2 602/4885SLC9A1 1705/4885ALOX5 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.