Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16603155 | 0.73 | MAOA (0.31) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL8331470 | 0.70 | NFE2L2 (0.43) | TDP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1637841 | 0.70 | MTNR1A (0.42) | TDP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL18573242 | 0.70 | AKT1 (0.39) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL17228550 | 0.69 | NPC1 (0.33) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL28002307 | 0.69 | MEN1 (0.41) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL20037284 | 0.69 | KDM1A (0.42) | TDP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL50199 | 0.68 | CES1 (0.47) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL23431996 | 0.67 | CA12 (0.41) | TDP1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL2270399 | 0.67 | TSHR (0.39) | TDP1ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |